Utility of adding clinical data to a molecular results portal for improving clinical trial prescreening efficiency.
Plain-language summary
This study evaluated whether adding minimal clinical data to a genomic results portal could make clinical trial prescreening more efficient for three molecularly driven trials at Vanderbilt-Ingram Cancer Center. Starting from 7,200 patients with sequencing data, gene-level and diagnosis criteria identified 68 potentially eligible patients; adding specific alteration detail removed 29% of them, and adding vital status removed an additional 42% of those remaining. The authors conclude that combining structured clinical and molecular data from the enterprise data warehouse improves prescreening efficiency and reduces manual chart review.
Read the full paper (DOI: 10.1200/JCO.2017.35.15_suppl.e18182).
This is a plain-language summary written for discoverability; the authoritative version is the published paper. Part of Travis Osterman's peer-reviewed publications.